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Assisted Hatching

In our IVF laboratory we can induce a successful embryo hatching with micromanipulations.

        Laser hatching


        Mechanical hatching

The human embryo is covered with a relatively firm shell (zona pellucida). It protects the embryo from adverse factors and makes it possible to maintain the relationship of its separate cells – blastomeres.

During the implantation process, i.e. embryo attachment to the endometrium, this shell is supposed to be shed, as if the embryo was “hatching” out of it. But this process can go wrong by the following reasons:

  • the shell is too thick,
  • the FSH level is too high,
  • the mother’s age factor is unfavourable,
  • the frozen embryos have been used. 

In our IVF laboratory conditions we facilitate the successful embryo hatching with the help of micromanipulations. We make a little hole in the embryo shell using a special microneedle (mechanical hatching) or a laser impulse (laser hatching). After that the embryo may easily leave the shell through this hole and begin the implantation.

Also the assisted hatching can be the integral part of the embryo biopsy used for the pre-implantation
genetic testing.

The doctors of our clinic presented their research concerning the assisted hatching at the Vth Congress of World Association of Reproductive Medicine 2010 – “ A Retrospective Evaluation of Mechanical and Laser Assisted Hatching” (Published by Reproductive BioMedicine Online 2010 October, Vol. 20, Supp. 3, p.S65)

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